Nature Communications (May 2022)

Signal requirement for cortical potential of transplantable human neuroepithelial stem cells

  • Balazs V. Varga,
  • Maryam Faiz,
  • Helena Pivonkova,
  • Gabriel Khelifi,
  • Huijuan Yang,
  • Shangbang Gao,
  • Emma Linderoth,
  • Mei Zhen,
  • Ragnhildur Thora Karadottir,
  • Samer M. Hussein,
  • Andras Nagy

DOI
https://doi.org/10.1038/s41467-022-29839-8
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 16

Abstract

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The regulatory pathways that control the human neural progenitor cell pool are not well understood. Here, Varga et al. identify signals that control the division of human pluripotent stem cell derived neural stem cells and their ability to make cortical neurons and glia.