Antifungal activity of Lantana camara L. and Syzygium aromaticum L. against Candida albicans

Abstract

Candida is a commensal organism found in 40-80% of normal humans. Candidiasis is observed in immunocompromised individuals such as HIV-positive patients, it may also occur in blood and genital tract. The drug-resistant bacteria and fungal pathogens have further complicated the treatment of infectious diseases in immunocompromised, AIDS and cancer patients. The in vitro antimicrobial activity was performed by Agar disc diffusion and Agar well diffusion method. The crude aqueous fractions and Methanolic extracts of leaves of Lantana camara and buds of Syzygium aromaticum were investigated for there antifungal activity against yeast Candida albicans. Methanolic extract of Syzygium was found to be effective against Candida while aqueous extract showed no activity. Both aqueous and methanolic extract of Lantana camara showed no antifungal activity. These observations could be the basis for the usefulness of the buds of Syzygium in treatment remedies for candidiasis or microbial infections.

Keywords

• Candida albicans
• Syzygium aromaticum
• Lantana camara
• Antifungal activity