Phase III, international, multicentre, double-blind, dose increment, parallel-arm, randomised controlled trial of duloxetine versus pregabalin for opioid-unresponsive neuropathic cancer pain: a JORTC-PAL16 trial protocol

• Takuhiro Yamaguchi,
• Tempei Miyaji,
• David C Currow,
• Jessica Lee,
• Jane Phillips,
• Slavica Kochovska,
• Brian Le,
• Melanie Lovell,
• Linda Brown,
• Belinda Fazekas,
• Meera Agar,
• Hiroto Ishiki,
• Eriko Satomi,
• Yoshinobu Matsuda,
• Keisuke Ariyoshi,
• Shunsuke Oyamada,
• Satoru Iwase,
• Katherine Clark,
• Hideaki Hasuo,
• Hiromichi Matsuoka,
• Atsuko Koyama,
• Peter Allcroft,
• Noriko Fujiwara

Affiliations

Takuhiro Yamaguchi

Division of Biostatistics, Tohoku University School of Medicine, Sendai, Miyagi, Japan

Tempei Miyaji

Innovation Center for Supportive, Palliative and Psychosocial Care, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan

David C Currow

MPACCT, Faculty of Health, University of Technology Sydney, Sydney, New South Wales, Australia

Jessica Lee

Department of Clinical Development, Foundation Medicine Inc, Cambridge, Massachusetts, USA

Jane Phillips

IMPACCT (Improving Palliative, Aged and Chronic Care through Clinical Research and Translation), University of Technology Sydney, Sydney, New South Wales, Australia

Slavica Kochovska

1 IMPACCT - Improving Palliative, Aged and Chronic Care through Clinical Research and Translation, University of Technology Sydney, Sydney, New South Wales, Australia

Brian Le

Palliative Care, The Royal Melbourne Hospital, Parkville, Victoria, Australia

Melanie Lovell

1 IMPACCT - Improving Palliative, Aged and Chronic Care through Clinical Research and Translation, University of Technology Sydney, Sydney, New South Wales, Australia

Linda Brown

1 IMPACCT - Improving Palliative, Aged and Chronic Care through Clinical Research and Translation, University of Technology Sydney, Sydney, New South Wales, Australia

Belinda Fazekas

3 IMPACCT, Faculty of Health, University of Technology Sydney, Sydney, New South Wales, Australia

Meera Agar

Faculty of Health, University of Technology Sydney, Sydney, New South Wales, Australia

Hiroto Ishiki

Department of Palliative Medicine, National Cancer Center Hospital, Tokyo, Japan

Eriko Satomi

Department of Palliative Medicine, National Cancer Center Hospital, Tokyo, Japan

Yoshinobu Matsuda

Department of Psychosomatic Internal Medicine, Kinki-Chuo Chest Medical Center, Sakai, Japan

Keisuke Ariyoshi

1 Department of Palliative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

Shunsuke Oyamada

6 Japanese Organisation for Research and Treatment of Cancer (JORTC), NPO, Tokyo, Japan

Satoru Iwase

1 Department of Palliative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

Katherine Clark

6 Northern Sydney Local Health District, Saint Leonards, New South Wales, Australia

Hideaki Hasuo

Psychosomatic Medicine, Kansai Medical University, Hirakata, Osaka, Japan

Hiromichi Matsuoka

1 Palliative Care Center, Cancer Center, Kindai University Hospital, Osaka, Japan

Atsuko Koyama

1 Palliative Care Center, Cancer Center, Kindai University Hospital, Osaka, Japan

Peter Allcroft

College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia

Noriko Fujiwara

Department of Palliative Medicine and Advanced Clinical Oncology, IMSUT Hospital of the Institute of Medical Science,The University of Tokyo, Japan, Tokyo, Japan