Nature Communications (Oct 2019)
Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus
Abstract
It is assumed that intracellular pathogenic bacteria must cope with DNA alkylating stress within host cells. Here, Poncin et al. show that the pathogen Brucella abortus does encounter alkylating stress within macrophages, and shed light into the pathways required for DNA repair in this organism.