A Randomized Comparison of two Short Intensive Chemotherapy Regimens in Children and Young Adults
With Osteosarcoma: Results in Patients With Metastases: A Study of the European Osteosarcoma Intergroup
Vivien H. C. Bramwell,
Marion V. Burgers,
Robert L. Souhami,
Antonie H. M. Taminiau,
Jan W. Van Der Eijken,
Alan W. Craft,
Archie J. Malcolm,
Barbara Uscinska,
Anna L. Kirkpatrick,
David Machin,
Martine M. Van Glabbeke
Affiliations
Vivien H. C. Bramwell
London Regional Cancer Centre, 790 Commissioners Road, East, London, Ontario N6A 4L6, Canada
Marion V. Burgers
Netherlands Cancer Institute, Amsterdam, The Netherlands
Robert L. Souhami
University College & Middlesex School of Medicine, London, UK
Antonie H. M. Taminiau
Academisch Ziekenhuis, Leiden, The Netherlands
Jan W. Van Der Eijken
Onze Lieve Vrouvwe Gasthuis, Amsterdam, The Netherlands
Purpose. To report the outcome of 37 patients with metastatic osteosarcoma entered into a large randomized trial (EOI 80831/MRC B002) comparing two different regimens of chemotherapy in patients with osteosarcoma.