Рациональная фармакотерапия в кардиологии (Dec 2015)

MYOCARDIAL DEFORMATION AND COMPLETE LEFT BUNDLE BRANCH BLOCK

  • E. N. Pavlyukova,
  • D. A. Kuzhel',
  • G. V. Matyushin,
  • N. S. Veselkova,
  • O. V. Avdeeva,
  • V. S. Metelitsa,
  • E. V. Samokhvalov,
  • E. A. Savchenko

DOI
https://doi.org/10.1234/1819-6446-2012-6-781-787
Journal volume & issue
Vol. 8, no. 6
pp. 781 – 787

Abstract

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Tissue Doppler imaging is evolving as a useful echocardiographic tool for quantitative assessment of left ventricular systolic and diastolic function. Over the last 10 years, myocardial deformation imaging has become possible initially with tissue Doppler , and more recently with myocardial speckle-tracking using 2D echocardiography. Unlike simple tissue velocity measurements, deformation measurements are specific for the region of interest. Strain rate or strain measurements have been used as sensitive indicators for subclinical diseases, and it is the most widely used tool to assess mechanical dyssynchrony. Left bundle branch block is a frequent, etiologically heterogeneous, clinically hostile and diagnostically challenging entity. About 2% of patients underwent cardiac stress testing show stable or intermittent left bundle branch block. Presence of left bundle branch block is associated with a lower and slower diastolic coronary flow velocity especially during hyperemia. Stress echocardiography is the best option for the diagnosis of ischemic heart disease, albeit specificity and sensitivity reduce in patients with left bundle branch block in the territory of left anterior descending artery in presence of initial septum dyskinesia.

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