A single-cell atlas and lineage analysis of the adult Drosophila ovary

Katja Rust; Laurean E. Byrnes; Kevin Shengyang Yu; Jason S. Park; Julie B. Sneddon; Aaron D. Tward; Todd G. Nystul

doi:10.1038/s41467-020-19361-0

Nature Communications (Nov 2020)

A single-cell atlas and lineage analysis of the adult Drosophila ovary

Katja Rust,
Laurean E. Byrnes,
Kevin Shengyang Yu,
Jason S. Park,
Julie B. Sneddon,
Aaron D. Tward,
Todd G. Nystul

Affiliations

Katja Rust: UCSF, Department of Anatomy
Laurean E. Byrnes: UCSF, Department of Anatomy
Kevin Shengyang Yu: UCSF, Department of Otolaryngology-Head and Neck Surgery
Jason S. Park: UCSF, Department of Otolaryngology-Head and Neck Surgery
Julie B. Sneddon: UCSF, Department of Anatomy
Aaron D. Tward: UCSF, Department of Otolaryngology-Head and Neck Surgery
Todd G. Nystul: UCSF, Department of Anatomy

DOI: https://doi.org/10.1038/s41467-020-19361-0
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 17

Abstract

Read online

Cell types in the adult Drosophila ovary vary during homeostasis and differing environmental conditions. Here, the authors use single-cell RNA-sequencing to identify 26 ovarian cell populations and show cellular plasticity in which escort cells can convert to follicle stem cells upon starvation.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal