Nature Communications (Dec 2022)
A Mycobacterium tuberculosis fingerprint in human breath allows tuberculosis detection
- Sergio Fabián Mosquera-Restrepo,
- Sophie Zuberogoïtia,
- Lucie Gouxette,
- Emilie Layre,
- Martine Gilleron,
- Alexandre Stella,
- David Rengel,
- Odile Burlet-Schiltz,
- Ana Cecilia Caro,
- Luis F. Garcia,
- César Segura,
- Carlos Alberto Peláez Jaramillo,
- Mauricio Rojas,
- Jérôme Nigou
Affiliations
- Sergio Fabián Mosquera-Restrepo
- Cellular Immunology and Immunogenetics Group (GICIG), Institute of Medical Research, Faculty of Medicine, University Research Headquarters (SIU), University of Antioquia (UdeA)
- Sophie Zuberogoïtia
- Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse, CNRS, University of Toulouse III-Paul Sabatier
- Lucie Gouxette
- Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse, CNRS, University of Toulouse III-Paul Sabatier
- Emilie Layre
- Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse, CNRS, University of Toulouse III-Paul Sabatier
- Martine Gilleron
- Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse, CNRS, University of Toulouse III-Paul Sabatier
- Alexandre Stella
- Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse, CNRS, University of Toulouse III-Paul Sabatier
- David Rengel
- Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse, CNRS, University of Toulouse III-Paul Sabatier
- Odile Burlet-Schiltz
- Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse, CNRS, University of Toulouse III-Paul Sabatier
- Ana Cecilia Caro
- Interdisciplinary Group for Molecular Studies (GIEM), Institute of Chemistry, Faculty of Exact and Natural Sciences. University of Antioquia (UdeA)
- Luis F. Garcia
- Cellular Immunology and Immunogenetics Group (GICIG), Institute of Medical Research, Faculty of Medicine, University Research Headquarters (SIU), University of Antioquia (UdeA)
- César Segura
- Malaria Group, University Research Headquarters, University of Antioquia (UdeA)
- Carlos Alberto Peláez Jaramillo
- Interdisciplinary Group for Molecular Studies (GIEM), Institute of Chemistry, Faculty of Exact and Natural Sciences. University of Antioquia (UdeA)
- Mauricio Rojas
- Cellular Immunology and Immunogenetics Group (GICIG), Institute of Medical Research, Faculty of Medicine, University Research Headquarters (SIU), University of Antioquia (UdeA)
- Jérôme Nigou
- Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse, CNRS, University of Toulouse III-Paul Sabatier
- DOI
- https://doi.org/10.1038/s41467-022-35453-5
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 15
Abstract
Most conventional tuberculosis diagnostic tests rely on difficult to obtain sputum samples. In this proof-of-concept study, authors analyse whether pulmonary tuberculosis can be detected using exhaled breath condensate samples.
