Clinical, Cosmetic and Investigational Dermatology (Aug 2023)
A Case of Secondary Syphilis with the Extragenital Chancre of the Lips and Tongue
Abstract
Dan Li,1 Ming Zhang,1 Jilai Yin,2,* Kai Chen1,* 1Department of Dermatology, The Fifth People’s Hospital of Hainan Province, Haikou, Hainan Province, People’s Republic of China; 2Department of Laboratory, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Kai Chen, Department of Dermatology, The Fifth People’s Hospital of Hainan Province, No. 8 Longhua Road, Longhua District, Haikou, Hainan Province, 570206, People’s Republic of China, Email [email protected] Jilai Yin, Department of Laboratory, the First Affiliated Hospital of Hainan Medical College, No. 31, Longhua Road, Haikou, Hainan Province, 570100, People’s Republic of China, Email [email protected]: A 18-year-old male presented with ulcers of lips and tongue and erythema of trunk of more than a month duration. Laboratory examinations for syphilis showed that TRUST (+) 1:32, TPPA (+), and HIV antibodies were negative. Combined with his case history and signs, he was diagnosed with secondary syphilis with chancre of lips and tongue and was cured by injecting benzathine penicillin 2.4 million U into gluteal muscles on both sides once a week for three times. After a month, the erythema and chancre disappeared. Three months later, the TRUST test was positive, the titer was 1:8, and the TPPA was positive.Keywords: chancre, secondary syphilis
