Squamous Carcinoma of the Oral Cavity in Patient with Fanconi Anemia: A Challenging Reconstruction with Double-barrel Free Fibula Flap Case Report

Maurizio Gargiulo, MD; Carlo Petroccione, MD; Sergio Razzano, MD; Francesca La Torre, MD; Vincenzo Manfellotto, MD; Giuseppe D’Aniello, MD; Gerarda Barbieri, MD; Matteo d’Alessio, MD; Giovanni Francesco Nicoletti, MD; Giuseppe Andrea Ferraro, PhD, MD

doi:10.1097/GOX.0000000000005414

Plastic and Reconstructive Surgery, Global Open (Nov 2023)

Squamous Carcinoma of the Oral Cavity in Patient with Fanconi Anemia: A Challenging Reconstruction with Double-barrel Free Fibula Flap Case Report

Maurizio Gargiulo, MD,
Carlo Petroccione, MD,
Sergio Razzano, MD,
Francesca La Torre, MD,
Vincenzo Manfellotto, MD,
Giuseppe D’Aniello, MD,
Gerarda Barbieri, MD,
Matteo d’Alessio, MD,
Giovanni Francesco Nicoletti, MD,
Giuseppe Andrea Ferraro, PhD, MD

Affiliations

Maurizio Gargiulo, MD: From the * Oro-Facial and Maxillo Surgery Department, “A. Cardarelli” Hospital, Napoli, Italy
Carlo Petroccione, MD: † Burn and Plastic, Reconstructive Unit, “A. Cardarelli” Hospital, Napoli, Italy
Sergio Razzano, MD: † Burn and Plastic, Reconstructive Unit, “A. Cardarelli” Hospital, Napoli, Italy
Francesca La Torre, MD: † Burn and Plastic, Reconstructive Unit, “A. Cardarelli” Hospital, Napoli, Italy
Vincenzo Manfellotto, MD: ‡ Plastic, Reconstructive and Aesthetic Surgery Unit, Campania University “L. Vanvitelli,” Napoli, Italy.
Giuseppe D’Aniello, MD: ‡ Plastic, Reconstructive and Aesthetic Surgery Unit, Campania University “L. Vanvitelli,” Napoli, Italy.
Gerarda Barbieri, MD: ‡ Plastic, Reconstructive and Aesthetic Surgery Unit, Campania University “L. Vanvitelli,” Napoli, Italy.
Matteo d’Alessio, MD: ‡ Plastic, Reconstructive and Aesthetic Surgery Unit, Campania University “L. Vanvitelli,” Napoli, Italy.
Giovanni Francesco Nicoletti, MD: ‡ Plastic, Reconstructive and Aesthetic Surgery Unit, Campania University “L. Vanvitelli,” Napoli, Italy.
Giuseppe Andrea Ferraro, PhD, MD: ‡ Plastic, Reconstructive and Aesthetic Surgery Unit, Campania University “L. Vanvitelli,” Napoli, Italy.

DOI: https://doi.org/10.1097/GOX.0000000000005414
Journal volume & issue: Vol. 11, no. 11
p. e5414

Abstract

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Summary:. Fanconi anemia (FA) is a very rare form of aplastic anemia. Patients with FA have a higher risk of developing solid tumors such as head and neck squamous cell carcinoma, higher risk of local recurrence, and impaired resistance to chemotherapy and radiotherapy treatments than the normal population. In this article, we describe the challenging clinical case of a patient with FA who underwent surgery for the removal of a large squamous cell carcinoma in the oral cavity. Mandibular reconstruction was performed using a biaxial double-barrel fibular flap, with excellent functional aesthetic outcomes.

Published in Plastic and Reconstructive Surgery, Global Open

ISSN: 2169-7574 (Online)
Publisher: Wolters Kluwer
Country of publisher: United States
LCC subjects: Medicine: Surgery
Website: http://www.prsgo.com

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