Nature Communications (Jun 2021)
Ultra-strong bio-glue from genetically engineered polypeptides
- Chao Ma,
- Jing Sun,
- Bo Li,
- Yang Feng,
- Yao Sun,
- Li Xiang,
- Baiheng Wu,
- Lingling Xiao,
- Baimei Liu,
- Vladislav S. Petrovskii,
- Bin Liu,
- Jinrui Zhang,
- Zili Wang,
- Hongyan Li,
- Lei Zhang,
- Jingjing Li,
- Fan Wang,
- Robert Gӧstl,
- Igor I. Potemkin,
- Dong Chen,
- Hongbo Zeng,
- Hongjie Zhang,
- Kai Liu,
- Andreas Herrmann
Affiliations
- Chao Ma
- Department of Chemistry, Tsinghua University
- Jing Sun
- School of Engineering and Applied Sciences, Harvard University
- Bo Li
- State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
- Yang Feng
- State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
- Yao Sun
- State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
- Li Xiang
- Department of Chemical and Materials Engineering, University of Alberta
- Baiheng Wu
- Institute of Process Equipment, College of energy engineering, Zhejiang University
- Lingling Xiao
- State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
- Baimei Liu
- State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
- Vladislav S. Petrovskii
- Physics Department, Lomonosov Moscow State University
- Bin Liu
- State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
- Jinrui Zhang
- State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
- Zili Wang
- State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
- Hongyan Li
- Zernike Institute for Advanced Materials, University of Groningen
- Lei Zhang
- State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
- Jingjing Li
- State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
- Fan Wang
- State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
- Robert Gӧstl
- DWI - Leibniz Institute for Interactive Materials
- Igor I. Potemkin
- Physics Department, Lomonosov Moscow State University
- Dong Chen
- Institute of Process Equipment, College of energy engineering, Zhejiang University
- Hongbo Zeng
- Department of Chemical and Materials Engineering, University of Alberta
- Hongjie Zhang
- Department of Chemistry, Tsinghua University
- Kai Liu
- Department of Chemistry, Tsinghua University
- Andreas Herrmann
- Zernike Institute for Advanced Materials, University of Groningen
- DOI
- https://doi.org/10.1038/s41467-021-23117-9
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 14
Abstract
Biomedical glues often face a challenge in providing strong adhesion and providing remodelling capabilities. Here the authors report on the development of a biocompatible and biodegradable protein-based coacervate adhesive and demonstrate application in haemostasis and wound healing using pig models.