Cytotoxic Activity of Metal Nanoparticle Complexes

Abstract

Metal complexes are widely used in pharmaceutics, cosmetics, electronics, casting printing and power generation. One of the major challenges due to their long-term use as medicines is their accumulation in the body. This issue needs to be resolved to achieve better results of metal complexes as medicines. The use of metal-nanoparticles (MNPs) can be expected to reduce the toxicity of metals and their accumulation in the body. The aim of this paper is to give an insight into the variation induced in the cytotoxic activity of MNP–ligand complexes by replacing the respective heavy metals with their nanoparticles (NPs).

Keywords

• nanoparticles
• metal-NPs complexes
• coordination
• cytotoxicity
• therapeutics
• targeting strategies