Thyroid dysfunction and kidney diseases

Abstract

Thyroid hormones provide normal functioning of the kidneys, which in turn are not only an organ for the metabolism and excretion of thyroid hormones but also serve as targets for the action of certain thyroid hormones. Hypothyroidism and hyperthyroidism are associated with clinically significant changes in the activity of the kidneys. Hypothyroidism is accompanied by a decrease in glomerular filtration rate (GFR), hyponatremia and a change in the ability to excrete water from the body through the kidney. Elevated levels of thyroid hormones lead to an increase in GFR and renal blood flow. Renal failure affects thyroid function. Chronic kidney disease is accompanied by noticeable effects on the hypothalamus-pituitary-thyroid axis. There is a link between thyroid cancer and kidney tumors. Recent studies show that thyroid hormones, especially T3, can be considered as a marker of survival in patients with kidney disease.

Keywords

• thyroid dysfunction
• hypothyroidism
• hyperthyroidism
• chronic kidney disease
• kidney failure