Эпидемиология и вакцинопрофилактика (Apr 2015)

Influence of Bacillus anthracis 34F<sub>2</sub> Sterne Antigen Preparations in Combination with Cobaltarabinogalactan on the Subpopulation Structure of B-lymphocytes (Communication 2)

  • V. V. Voytkova,
  • V. I. Dubrovina,
  • S. V. Lukyanov,
  • O. V. Yuryeva,
  • O. B. Kol’Esnikova,
  • K. M. Korytov,
  • G. P. Aleksandrova,
  • V. P. Iljin,
  • S. V. Balakhonov

DOI
https://doi.org/10.31631/2073-3046-2015-14-2-107-112
Journal volume & issue
Vol. 14, no. 2
pp. 107 – 112

Abstract

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Study of Bacillus anthracis 34F2 Sterne antigenic preparation S-2 and its combined use with nanostructured cobalt-arabinogalaktan (Со-АG) is presented. The ability of these preparations to stimulate proliferation and differentiation of B-lymphocytes is demonstrated. However, content of the B-lymphocyte circulating subpopulations depends on the time of observation. Co-AG exhibits adjuvant properties enhanced the immunogenic features of the S-2 B. anthracis 34F2 Sterne that may indicate its availability as an adjuvant in the construction of chemical vaccines.

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