Nature Communications (Jul 2021)
The trans-omics landscape of COVID-19
- Peng Wu,
- Dongsheng Chen,
- Wencheng Ding,
- Ping Wu,
- Hongyan Hou,
- Yong Bai,
- Yuwen Zhou,
- Kezhen Li,
- Shunian Xiang,
- Panhong Liu,
- Jia Ju,
- Ensong Guo,
- Jia Liu,
- Bin Yang,
- Junpeng Fan,
- Liang He,
- Ziyong Sun,
- Ling Feng,
- Jian Wang,
- Tangchun Wu,
- Hao Wang,
- Jin Cheng,
- Hui Xing,
- Yifan Meng,
- Yongsheng Li,
- Yuanliang Zhang,
- Hongbo Luo,
- Gang Xie,
- Xianmei Lan,
- Ye Tao,
- Jiafeng Li,
- Hao Yuan,
- Kang Huang,
- Wan Sun,
- Xiaobo Qian,
- Zhichao Li,
- Mingxi Huang,
- Peiwen Ding,
- Haoyu Wang,
- Jiaying Qiu,
- Feiyue Wang,
- Shiyou Wang,
- Jiacheng Zhu,
- Xiangning Ding,
- Chaochao Chai,
- Langchao Liang,
- Xiaoling Wang,
- Lihua Luo,
- Yuzhe Sun,
- Ying Yang,
- Zhenkun Zhuang,
- Tao Li,
- Lei Tian,
- Shaoqiao Zhang,
- Linnan Zhu,
- Ashley Chang,
- Lei Chen,
- Yiquan Wu,
- Xiaoyan Ma,
- Fang Chen,
- Yan Ren,
- Xun Xu,
- Siqi Liu,
- Jian Wang,
- Huanming Yang,
- Lin Wang,
- Chaoyang Sun,
- Ding Ma,
- Xin Jin,
- Gang Chen
Affiliations
- Peng Wu
- Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology
- Dongsheng Chen
- BGI-Shenzhen
- Wencheng Ding
- Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology
- Ping Wu
- Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology
- Hongyan Hou
- Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
- Yong Bai
- BGI-Shenzhen
- Yuwen Zhou
- BGI-Shenzhen
- Kezhen Li
- Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology
- Shunian Xiang
- BGI-Shenzhen
- Panhong Liu
- BGI-Shenzhen
- Jia Ju
- BGI-Shenzhen
- Ensong Guo
- Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology
- Jia Liu
- Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology
- Bin Yang
- Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology
- Junpeng Fan
- Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology
- Liang He
- Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology
- Ziyong Sun
- Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
- Ling Feng
- Department of Gynecology and Obstetrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology
- Jian Wang
- Department of Clinical Laboratory, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
- Tangchun Wu
- Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology
- Hao Wang
- Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology
- Jin Cheng
- Department of Research, Xiangyang Central Hospital, Hubei University of Arts and Science, Xiangyang
- Hui Xing
- Department of Obstetrics and Gynecology, Xiangyang Central Hospital, Hubei University of Arts and Science, Xiangyang
- Yifan Meng
- Department of Gynecologic Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center
- Yongsheng Li
- Key Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan Medical University
- Yuanliang Zhang
- BGI-Shenzhen
- Hongbo Luo
- BGI-Shenzhen
- Gang Xie
- BGI-Shenzhen
- Xianmei Lan
- BGI-Shenzhen
- Ye Tao
- BGI-Shenzhen
- Jiafeng Li
- BGI-Shenzhen
- Hao Yuan
- BGI-Shenzhen
- Kang Huang
- BGI-Shenzhen
- Wan Sun
- BGI-Shenzhen
- Xiaobo Qian
- BGI-Shenzhen
- Zhichao Li
- BGI-Shenzhen
- Mingxi Huang
- BGI-Shenzhen
- Peiwen Ding
- BGI-Shenzhen
- Haoyu Wang
- BGI-Shenzhen
- Jiaying Qiu
- BGI-Shenzhen
- Feiyue Wang
- BGI-Shenzhen
- Shiyou Wang
- BGI-Shenzhen
- Jiacheng Zhu
- BGI-Shenzhen
- Xiangning Ding
- BGI-Shenzhen
- Chaochao Chai
- BGI-Shenzhen
- Langchao Liang
- BGI-Shenzhen
- Xiaoling Wang
- BGI-Shenzhen
- Lihua Luo
- BGI-Shenzhen
- Yuzhe Sun
- BGI-Shenzhen
- Ying Yang
- BGI-Shenzhen
- Zhenkun Zhuang
- BGI-Shenzhen
- Tao Li
- BGI-Shenzhen
- Lei Tian
- BGI-Shenzhen
- Shaoqiao Zhang
- BGI-Hubei, BGI-Shenzhen
- Linnan Zhu
- BGI-Shenzhen
- Ashley Chang
- BGI-Shenzhen
- Lei Chen
- College of Veterinary Medicine, Yangzhou University
- Yiquan Wu
- HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health
- Xiaoyan Ma
- Department of Biochemistry, University of Cambridge
- Fang Chen
- BGI-Shenzhen
- Yan Ren
- BGI-Shenzhen
- Xun Xu
- BGI-Shenzhen
- Siqi Liu
- BGI-Shenzhen
- Jian Wang
- BGI-Shenzhen
- Huanming Yang
- BGI-Shenzhen
- Lin Wang
- Department of Clinical Laboratory, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
- Chaoyang Sun
- Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology
- Ding Ma
- Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology
- Xin Jin
- BGI-Shenzhen
- Gang Chen
- Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology
- DOI
- https://doi.org/10.1038/s41467-021-24482-1
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 16
Abstract
COVID-19 is a critical public health threat, but molecular characterizations of patients’ immunity is still lacking. Here the authors collected blood from patients with various disease severity, and prefiltered to exclude selected comorbidity, to obtain genomic, transcriptomic, proteomic, metabolomic and lipidomic profiles to report a trans-omics landscape.
