Acta Medica Iranica (Nov 2018)

Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1

  • Ahmad Bahrami,
  • Mahnaz Sadeghian,
  • Mehrdad Sheikhvatan,
  • Arash Foroudi,
  • Sara Harsini,
  • Nima Rezaei

Journal volume & issue
Vol. 56, no. 8

Abstract

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Leukocyte adhesion deficiency type 1 (LAD-1) is a rare autosomal recessive immunodeficiency disorder, characterized by recurrent bacterial and fungal infections without pus formation. Herein, we report a case of LAD-1 that developed into gastrointestinal cytomegalovirus (CMV) disease and manifested with persistent abdominal pain and bloody diarrhea. Although the presence of concurrent gastrointestinal CMV infection with LAD-1 is a rare condition, this case highlights the need for further research to evaluate the complex mechanisms between LAD-1 and CMV occurrence.

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