Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity

Natalia I. Moguillansky, MD; Hafiz Abdul Moiz Fakih, MD; John R. Wingard, MD

doi:10.1016/j.rmcr.2017.05.003

Respiratory Medicine Case Reports (Jan 2017)

Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity

Natalia I. Moguillansky, MD,
Hafiz Abdul Moiz Fakih, MD,
John R. Wingard, MD

Affiliations

Natalia I. Moguillansky, MD: University of Florida, Pulmonary, Critical Care and Sleep Medicine, P.O. Box 100225 JHMHC, Gainesville, FL 32610-0225, USA
Hafiz Abdul Moiz Fakih, MD: University of Florida, Pulmonary, Critical Care and Sleep Medicine, P.O. Box 100225 JHMHC, Gainesville, FL 32610-0225, USA
John R. Wingard, MD: University of Florida, UF Health Bone Marrow Transplant – Shands Hospital, 1515 SW Archer Rd, Suite #100, Gainesville, FL 32608, USA

DOI: https://doi.org/10.1016/j.rmcr.2017.05.003
Journal volume & issue: Vol. 21, no. C
pp. 154 – 157

Abstract

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Tyrosine kinase inhibitors are known to cause pulmonary complications. We report a case of bosutinib related bilateral pleural effusions in a patient with chronic myeloid leukemia. Characteristics of the pleural fluid are presented. We also discuss other tyrosine kinase inhibitors induced pulmonary toxicities, including pulmonary hypertension and interstitial lung disease.

Published in Respiratory Medicine Case Reports

ISSN: 2213-0071 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: https://www.sciencedirect.com/journal/respiratory-medicine-case-reports

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