Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling

Gongyu Li; Fengfei Ma; Qinjingwen Cao; Zhen Zheng; Kellen DeLaney; Rui Liu; Lingjun Li

doi:10.1038/s41467-019-12548-0

Nature Communications (Oct 2019)

Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling

Gongyu Li,
Fengfei Ma,
Qinjingwen Cao,
Zhen Zheng,
Kellen DeLaney,
Rui Liu,
Lingjun Li

Affiliations

Gongyu Li: School of Pharmacy, University of Wisconsin-Madison
Fengfei Ma: School of Pharmacy, University of Wisconsin-Madison
Qinjingwen Cao: Department of Chemistry, University of Wisconsin-Madison
Zhen Zheng: School of Pharmacy, University of Wisconsin-Madison
Kellen DeLaney: Department of Chemistry, University of Wisconsin-Madison
Rui Liu: School of Pharmacy, University of Wisconsin-Madison
Lingjun Li: School of Pharmacy, University of Wisconsin-Madison

DOI: https://doi.org/10.1038/s41467-019-12548-0
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 11

Abstract

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Mass spectrometry-based quantitative proteomics aim to identify and quantify proteins from complex biological samples. Here, the authors developed a method for simultaneous high-throughput protein labelling and on-demand matrix removal within nanoseconds.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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