High-resolution in situ analysis of Cas9 germline transcript distributions in gene-drive Anopheles mosquitoes

Gerard Terradas; Anita Hermann; Anthony A James; William McGinnis; Ethan Bier

doi:10.1093/g3journal/jkab369

G3: Genes, Genomes, Genetics (Nov 2021)

High-resolution in situ analysis of Cas9 germline transcript distributions in gene-drive Anopheles mosquitoes

Gerard Terradas,
Anita Hermann,
Anthony A James,
William McGinnis,
Ethan Bier

Affiliations

Gerard Terradas: Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093, USA
Anita Hermann: Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093, USA
Anthony A James: ORCiD; Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697, USA
William McGinnis: Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093, USA
Ethan Bier: ORCiD; Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093, USA

DOI: https://doi.org/10.1093/g3journal/jkab369
Journal volume & issue: Vol. 12, no. 1

Abstract

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AbstractGene drives are programmable genetic elements that can spread beneficial traits into wild populations to aid in vector-borne pathogen control. Two different drives have been developed for population modification of mosquito vectors. The ReckhvasaAnopheles stephensiAgNosCd-1nosAnopheles gambiae

Published in G3: Genes, Genomes, Genetics

ISSN: 2160-1836 (Online)
Publisher: Oxford University Press
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General): Genetics
Website: https://academic.oup.com/g3journal

About the journal