Synchronous or metachronous metastatic cutaneous cell carcinoma and lymphoma/cronic lymphocytic leukaemia: Considerations for management

Valentina Terenzi; Veronica Clemenzi; Salvatore Martellucci; Andrea Stolfa; Fiorenza Dal Cortivo; Danilo Di Giorgio; Alberto DellAquila; Mattia Di Bartolomeo; Marco Della Monaca; Andrea Battisti; Paolo Priore; Andrea Gallo; Valentino Valentini; Giulio Pagliuca

Oral Oncology Reports (Mar 2025)

Synchronous or metachronous metastatic cutaneous cell carcinoma and lymphoma/cronic lymphocytic leukaemia: Considerations for management

Valentina Terenzi,
Veronica Clemenzi,
Salvatore Martellucci,
Andrea Stolfa,
Fiorenza Dal Cortivo,
Danilo Di Giorgio,
Alberto DellAquila,
Mattia Di Bartolomeo,
Marco Della Monaca,
Andrea Battisti,
Paolo Priore,
Andrea Gallo,
Valentino Valentini,
Giulio Pagliuca

Affiliations

Valentina Terenzi: Surgical Sciences Department, “Tor Vergata” University, Rome, Italy; UOSD Maxillo-Facial Surgery, Policlinico Tor Vergata, Italy; Corresponding author. Via Mario Fascetti, 5-00136, Rome, Italy.
Veronica Clemenzi: Department of Sense Organs, ENT Section, “Sapienza” University of Rome, Italy
Salvatore Martellucci: Otolaryngology University Unit, “S.M. Goretti Hospital”, Latina, Italy
Andrea Stolfa: Department of Sense Organs, ENT Section, “Sapienza” University of Rome, Italy
Fiorenza Dal Cortivo: Department of Odontostomatological and Maxillo-Facial Sciences, “Sapienza” University of Rome, Italy
Danilo Di Giorgio: Department of Odontostomatological and Maxillo-Facial Sciences, “Sapienza” University of Rome, Italy
Alberto DellAquila: Department of Odontostomatological and Maxillo-Facial Sciences, “Sapienza” University of Rome, Italy
Mattia Di Bartolomeo: Department of Odontostomatological and Maxillo-Facial Sciences, “Sapienza” University of Rome, Italy
Marco Della Monaca: Department of Odontostomatological and Maxillo-Facial Sciences, “Sapienza” University of Rome, Italy
Andrea Battisti: Department of Odontostomatological and Maxillo-Facial Sciences, “Sapienza” University of Rome, Italy
Paolo Priore: Department of Odontostomatological and Maxillo-Facial Sciences, “Sapienza” University of Rome, Italy
Andrea Gallo: Department of Sense Organs, ENT Section, “Sapienza” University of Rome, Italy; Otolaryngology University Unit, “S.M. Goretti Hospital”, Latina, Italy
Valentino Valentini: Department of Odontostomatological and Maxillo-Facial Sciences, “Sapienza” University of Rome, Italy
Giulio Pagliuca: Department of Sense Organs, ENT Section, “Sapienza” University of Rome, Italy

Journal volume & issue: Vol. 13
p. 100703

Abstract

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Cutaneous squamous cell carcinoma is not uncommon in patients affected by malignant lymphoma, mostly in elderly; the contemporary management of these diseases presents some difficulties, since they require different modalities of treatment. Only small case series and single case report are described in literature about synchronous or metachronous metastatic cutaneous cell carcinoma and lymphoma/chronic lymphocytic leukaemia; in addiction, we report our experience in order to illustrate difficulties encountered in the management of these patients. We conclude that these patients need a close follow-up, and that US-guided FNAC and 18F-fluorodeoxyglucose PET in addiction to MRI are useful for staging. cSCC, having a poorer prognosis, has to be treated first; nevertheless, mortality in these patients is obviously higher than expected in immunocompetent people.

Published in Oral Oncology Reports

ISSN: 2772-9060 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.sciencedirect.com/journal/oral-oncology-reports

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