NEW LOOK ON SPECIFIC IMMUNOTHERAPY IN CHILDREN

Abstract

Objective of the Review: introduce modern ideas about the allergen-specific immunotherapy (ASIT) in children.Key Points: The article presents data about frequency of sensibilization and allergic respiratory diseases in children. House dust mites and pollens are considered a major risk factors of allergic sensitization which plays an important role in development of allergic rhinitis and bronchial asthma. Allergen avoidance and pharmacotherapy cannot control the disease. Only allergy immunotherapy has disease-modifying potential and should be included in optimal treatment strategies for children. Allergy immunotherapy was first administered as subcutaneous injections. Recently, sublingual allergy immunotherapy (SLIT) was introduced. SLIT represent a more patient-friendly method because it can be used for children treatment at home.Conclusion: The allergen-specific immunotherapy is safe, effective method for treatment of children with allergic respiratory disease. Sublingual allergy immunotherapy optimizes the opportunity as noninvasive patient-friendly concept.

Keywords

• asthma
• allergic rhinitis
• allergen-specific immunotherapy
• efficiency
• safety