Zhongguo linchuang yanjiu (Feb 2024)
Prognosis of 111 young patients with hypertensive intracerebral hemorrhage: a single center clinical study
Abstract
Objective To explore the differences in prognosis of young hypertensive intracerebral hemorrhage (HIH) patients with different age, gender, and bleeding sites. Methods A retrospective analysis of 111 young HIH patients admitted to Shandong Second Provincal General Hospital from October 2016 to October 2021 was conducted. The patients were divided into 24-34 age group (47 cases) and 35-45 age group (64 cases) according to age. The patients were divided into male group (60 cases) and female group (51 cases) according to gender. After excluding the compound hemorrhage (18 cases), patients were divided into basal ganglia hemorrhage group (39 cases), brainstem hemorrhage group (26 cases), and intraventricular hemorrhage group (28 cases) according to the location of bleeding. Glasgow Outcome Scale (GOS), National Institutes of Health Neurological Deficit Scale (NIHSS), and long-term Karnofsky Performance Status (KPS) were compared among patients in different age groups, gender groups, and bleeding site groups at 1, 3, and 12 months after treatment. Results There was no significant difference in scores of GOS, NIHSS and KPS at 1 and 3 months between 24-34 age group and 35-45 age group (P＞0.05). The 12-month GOS, NIHSS and KPS scores of the 24-34 age group were significantly higher than those of the 35-45 age group (P＜0.05). There was no significant difference in GOS, NIHSS and KPS scores between male group and female group at 1, 3 and 12 months (P＞0.05). The scores of GOS, NIHSS and KPS in basal ganglia hemorrhage group were better than those in brainstem hemorrhage group and intraventricular hemorrhage group at 1 and 3 months, and the scores of GOS, NIHSS and KPS in brainstem hemorrhage group were better than those in basal ganglia hemorrhage group and intraventricular hemorrhage group at 12 months (P＜0.05). Conclusion The short-term prognosis of young patients with HIH is not directly related to age. But for the long-term prognosis, the younger the better. There is no correlation between the prognosis and gender in HIH in young people. The short-term prognosis of basal ganglia cerebral hemorrhage is better than brainstem hemorrhage and intraventricular hemorrhage. The long-term prognosis of brain stem hemorrhage is better than basal ganglia hemorrhage and intraventricular hemorrhage.
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