Nature Communications (Jul 2017)
Bayesian association scan reveals loci associated with human lifespan and linked biomarkers
- Aaron F. McDaid,
- Peter K. Joshi,
- Eleonora Porcu,
- Andrea Komljenovic,
- Hao Li,
- Vincenzo Sorrentino,
- Maria Litovchenko,
- Roel P. J. Bevers,
- Sina Rüeger,
- Alexandre Reymond,
- Murielle Bochud,
- Bart Deplancke,
- Robert W. Williams,
- Marc Robinson-Rechavi,
- Fred Paccaud,
- Valentin Rousson,
- Johan Auwerx,
- James F. Wilson,
- Zoltán Kutalik
Affiliations
- Aaron F. McDaid
- Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital
- Peter K. Joshi
- Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh
- Eleonora Porcu
- Swiss Institute of Bioinformatics
- Andrea Komljenovic
- Swiss Institute of Bioinformatics
- Hao Li
- Laboratory of Integrative and Systems Physiology, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL)
- Vincenzo Sorrentino
- Laboratory of Integrative and Systems Physiology, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL)
- Maria Litovchenko
- Swiss Institute of Bioinformatics
- Roel P. J. Bevers
- Swiss Institute of Bioinformatics
- Sina Rüeger
- Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital
- Alexandre Reymond
- Center for Integrative Genomics, University of Lausanne
- Murielle Bochud
- Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital
- Bart Deplancke
- Swiss Institute of Bioinformatics
- Robert W. Williams
- Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center
- Marc Robinson-Rechavi
- Swiss Institute of Bioinformatics
- Fred Paccaud
- Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital
- Valentin Rousson
- Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital
- Johan Auwerx
- Laboratory of Integrative and Systems Physiology, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL)
- James F. Wilson
- Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh
- Zoltán Kutalik
- Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital
- DOI
- https://doi.org/10.1038/ncomms15842
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 11
Abstract
Along with various environmental factors, a complex genetic architecture influences human lifespan. Here, McDaid and colleagues reveal novel loci associated with human lifespan and linked biomarkers by Bayesian association scan.
