From Bench to Bedside: What Do We Know about Imidazothiazole Derivatives So Far?

Abstract

Imidazothiazole derivatives are becoming increasingly important in therapeutic use due to their outstanding physiological activities. Recently, applying imidazothiazole as the core, researchers have synthesized a series of derivatives with biological effects such as antitumor, anti-infection, anti-inflammatory and antioxidant effects. In this review, we summarize the main pharmacological effects and pharmacological mechanisms of imidazothiazole derivates; the contents summarized herein are intended to advance the research and rational development of imidazothiazole-based drugs in the future.

Keywords

• condensed heterocyclic compounds
• imidazothiazoles
• pharmacological effect
• druggable candidates
• levamisole