Bayesian stroke modeling details sex biases in the white matter substrates of aphasia

Julius M. Kernbach; Gesa Hartwigsen; Jae-Sung Lim; Hee-Joon Bae; Kyung-Ho Yu; Gottfried Schlaug; Anna Bonkhoff; Natalia S. Rost; Danilo Bzdok

doi:10.1038/s42003-023-04733-1

Communications Biology (Mar 2023)

Bayesian stroke modeling details sex biases in the white matter substrates of aphasia

Julius M. Kernbach,
Gesa Hartwigsen,
Jae-Sung Lim,
Hee-Joon Bae,
Kyung-Ho Yu,
Gottfried Schlaug,
Anna Bonkhoff,
Natalia S. Rost,
Danilo Bzdok

Affiliations

Julius M. Kernbach: Neurosurgical Artificial Intelligence Laboratory Aachen (NAILA), RWTH Aachen University Hospital
Gesa Hartwigsen: Max Planck Institute for Human Cognitive and Brain Sciences, Lise Meitner Research Group Cognition and Plasticity
Jae-Sung Lim: Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine
Hee-Joon Bae: Department of Neurology, Cerebrovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine
Kyung-Ho Yu: Department of Neurology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine
Gottfried Schlaug: Music, Neuroimaging, and Stroke Recovery Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School
Anna Bonkhoff: J. Philip Kistler Stroke Research Center, Massachusetts General Hospital, Harvard Medical School
Natalia S. Rost: J. Philip Kistler Stroke Research Center, Massachusetts General Hospital, Harvard Medical School
Danilo Bzdok: Department of Biomedical Engineering, McConnell Brain Imaging Centre, Montreal Neurological Institute, Faculty of Medicine, School of Computer Science, McGill University

DOI: https://doi.org/10.1038/s42003-023-04733-1
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 17

Abstract

Read online

Bayesian modeling of anatomical lesion patterns and clinical language outcomes in a cohort of 1401 stroke patients identifies sex-biased lesion-outcome effects after stroke.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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