Virus-borne mini-CRISPR arrays are involved in interviral conflicts

Sofia Medvedeva; Ying Liu; Eugene V. Koonin; Konstantin Severinov; David Prangishvili; Mart Krupovic

doi:10.1038/s41467-019-13205-2

Nature Communications (Nov 2019)

Virus-borne mini-CRISPR arrays are involved in interviral conflicts

Sofia Medvedeva,
Ying Liu,
Eugene V. Koonin,
Konstantin Severinov,
David Prangishvili,
Mart Krupovic

Affiliations

Sofia Medvedeva: Institut Pasteur, Department of Microbiology
Ying Liu: Institut Pasteur, Department of Microbiology
Eugene V. Koonin: National Center for Biotechnology Information, National Library of Medicine
Konstantin Severinov: Center of Life Sciences, Skolkovo Institute of Science and Technology
David Prangishvili: Institut Pasteur, Department of Microbiology
Mart Krupovic: Institut Pasteur, Department of Microbiology

DOI: https://doi.org/10.1038/s41467-019-13205-2
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 10

Abstract

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Here, the authors investigate the diversity and dynamics of the CRISPRome in the hyperthermophilic archaea of the order Sulfolobales, and find the most abundant spacers to come from mini-CRISPR arrays of archaeal viruses, which might represent a strategy for superinfection exclusion and promotion of archaeal virus speciation.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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