Parallel ventral hippocampus-lateral septum pathways differentially regulate approach-avoidance conflict

Dylan C. M. Yeates; Dallas Leavitt; Sajeevan Sujanthan; Nisma Khan; Denada Alushaj; Andy C. H. Lee; Rutsuko Ito

doi:10.1038/s41467-022-31082-0

Nature Communications (Jun 2022)

Parallel ventral hippocampus-lateral septum pathways differentially regulate approach-avoidance conflict

Dylan C. M. Yeates,
Dallas Leavitt,
Sajeevan Sujanthan,
Nisma Khan,
Denada Alushaj,
Andy C. H. Lee,
Rutsuko Ito

Affiliations

Dylan C. M. Yeates: Department of Psychology (Scarborough), University of Toronto
Dallas Leavitt: Department of Psychology (Scarborough), University of Toronto
Sajeevan Sujanthan: Department of Psychology (Scarborough), University of Toronto
Nisma Khan: Department of Psychology (Scarborough), University of Toronto
Denada Alushaj: Department of Psychology (Scarborough), University of Toronto
Andy C. H. Lee: Department of Psychology (Scarborough), University of Toronto
Rutsuko Ito: Department of Psychology (Scarborough), University of Toronto

DOI: https://doi.org/10.1038/s41467-022-31082-0
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 13

Abstract

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The ventral hippocampal CA3 and CA1 subfields play a critical role in the resolution of approach-avoidance conflict. Here the authors show that the subfields contribute to the regulation of this behavior through topographically distinct projections to the lateral septum.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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