Novel Human Rhinoviruses and Exacerbation of Asthma in Children

Abstract

To determine links between human rhinoviruses (HRV) and asthma, we used data from a case–control study, March 2003–February 2004, among children with asthma. Molecular characterization identified several likely new HRVs and showed that association with asthma exacerbations was largely driven by HRV-A and a phylogenetically distinct clade of 8 strains, genogroup C.

Keywords

• human rhinoviruses
• human rhinovirus genogroup C
• human rhinovirus species A
• human rhinovirus species B
• bronchial asthma
• rhinovirus PCR