Analysis of the SXT Constin of Antibiotic-Sensitive <I>Vibrio cholerae </I>Strain of Non-O1/ Non-O139 Serogroup

Abstract

In the genome of antibiotic-sensitive Vibrio cholerae strain belonging to O50 serogroup, isolated in the territory of the Russian Federation in 1974, detected is the SXT conjugative trasposone – SXT constin. Analysis if its structure revealed that it does not contain genes of resistance to such antibiotics as streptomycin, sulfamethoxasole, trimethoprim, chloramphenicol, and kanamycin, being, probably, one of the predecessors of antibiotic-resistant SXT constins which spread out within the genomes of epidemic Vibrio cholerae O139 strains in 1992.

Keywords

• возбудитель холеры
• геном
• устойчивость к антибиотикам
• cholera agent
• genome
• antibiotic resistance