Clinical value of serum amyloid A detection in the diagnosis of infective endophthalmitis

Abstract

AIM:To investigate the clinical value of serum amyloid A(SAA)in the diagnosis of infectious endophthalmitis. METHODS:A total of 270 patients admitted to the Eye Hospital of Wenzhou Medical University from June 2016 to March 2019 were collected, including 116 patients with infectious endophthalmitis as the experimental group and 154 non-infectious patients as the control group. The levels of SAA was detected by colloidal gold immunochromatography. Variables were compared and diagnostic value was measured by using receiver operating characteristic(ROC)curve.RESULTS:The median levels of SAA in experimental group and control group were 14.98mg/L and 2.56mg/L, respectively,the difference between the two groups was statistically significant(PPCONCLUSION: SAA combined with CRP and WBC can improve the diagnostic efficacy of infective endophthalmitis. SAA can provide useful reference information for the assistant diagnosis of infectious endophthalmitis, which is worthy of clinical application.

Keywords

• infection
• endophthalmitis
• serum amyloid A Protein
• C-reactive protein
• white blood cell count