The effect of high dose digoxin on cytokines in healthy dogs

Haluk  Dülger; Mehmet Ramazan Şekeroğlu; Beyhan  Eryonucu; Tevfik  Noyan; Süleyman  Alici

doi:10.1080/096293502900000122

Mediators of Inflammation (Jan 2002)

The effect of high dose digoxin on cytokines in healthy dogs

Haluk Dülger,
Mehmet Ramazan Şekeroğlu,
Beyhan Eryonucu,
Tevfik Noyan,
Süleyman Alici

Affiliations

Haluk Dülger: Department of Biochemistry, School of Medicine, University of Yüzüncü Yil, YüzüncüYil Üniversitesi, Tip Fakültesi, Biyokimya Anabilim Dali, Maraş Caddesi, Van 65300, Turkey
Mehmet Ramazan Şekeroğlu: Department of Cardiology, School of Medicine, University of Yüzüncü Yil, YüzüncüYil Üniversitesi, Tip Fakültesi, Biyokimya Anabilim Dali, Maraş Caddesi, Van 65300, Turkey
Beyhan Eryonucu: Department of Cardiology, School of Medicine, University of Yüzüncü Yil, YüzüncüYil Üniversitesi, Tip Fakültesi, Biyokimya Anabilim Dali, Maraş Caddesi, Van 65300, Turkey
Tevfik Noyan: Department of Biochemistry, School of Medicine, University of Yüzüncü Yil, YüzüncüYil Üniversitesi, Tip Fakültesi, Biyokimya Anabilim Dali, Maraş Caddesi, Van 65300, Turkey
Süleyman Alici: Department of Internal Medicine, School of Medicine, University of Yüzüncü Yil, YüzüncüYil Üniversitesi, Tip Fakültesi, Biyokimya Anabilim Dali, Maraş Caddesi, Van 65300, Turkey

DOI: https://doi.org/10.1080/096293502900000122
Journal volume & issue: Vol. 11, no. 4
pp. 261 – 263

Abstract

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Background: Tumor necrosis factor (TNF)-α and interleukin (IL)-1β are pro-inflammatory cytokines, causing myocardial dysfunction and a negative inotropic effect. The drugs used to treat heart failure affect the production of cytokines. Digoxin, on which this study was focused, is one of the drugs for the treatment of heart failure.

Published in Mediators of Inflammation

ISSN: 0962-9351 (Print); 1466-1861 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Pathology
Website: https://www.hindawi.com/journals/mi/

About the journal