中西医结合护理 (Jun 2022)

A correlation analysis between the distributions of TCM constitutional types of patients with mammary cancer and anxiety and depression status (乳腺癌患者中医体质类型分布及其与焦虑抑郁的相关性分析)

  • ZI Yuxia (资雨霞),
  • LI Li (李莉),
  • YOU Dingyun (游顶云),
  • ZHANG Zhihua (张志华),
  • MA Qiong (马琼),
  • HEI Chunyan (黑春燕),
  • CHEN Limin (陈立敏),
  • LI Julin (李菊林),
  • LI Ya (李娅)

DOI
https://doi.org/10.55111/j.issn2709-1961.202204060
Journal volume & issue
Vol. 8, no. 6
pp. 66 – 72

Abstract

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Objective To explore the relationship between the distributions of traditional Chinese medicine (TCM) constitutional types of patients with mammary cancer and their anxiety and depression status. Methods A total of 507 patients with mammary cancer who were admitted and treated in Yunnan Cancer Hospital from July 2019 to July 2020 were selected. Baseline data were collected through questionnaires, and the Constitution in Chinese Medicine Questionnaire (CCMQ) was used to identify their TCM constitutions. Hospital Anxiety and Depression Scale (HADS) was used for assessing the anxiety and depression status of patients. Results Totally 398 patients with mammary cancer were screened. Most of the mammary cancer patients had normal constitution, 136(34. 17%) in total, followed by 80(20. 10%) cases with yang-deficiency constitution, 39(9. 80%) cases with yin-deficiency constitution and 38 (9. 55%)cases with qi depression constitution. There were 75(18. 84%) patients with depression and 89(22. 36%) patients with anxiety. Patients who had normal constitutional types were control group. Except for dampness-heat constitution and yang-deficiency constitution, the other six biased constitutions were all risk factors for the onset of depression. Among them, the top three are blood stasis constitution (OR=14. 71, P<0. 001), qi deficiency constitution (OR=7. 69, P<0. 001), yin-deficiency constitution (OR=6. 20, P<0. 001); all biased constitutions are risky factors for the onset of anxiety. The top three constitutions that are most closely related to the onset of anxiety are: blood stasis constitution (OR=17. 41, P<0. 001), yin-deficiency constitution (OR=14. 05, P<0. 001), phlegm-dampness constitution (OR=14. 02, P<0. 001). Conclusion Normal constitution and yang-deficiency constitution are the most common TCM constitutional types for patients with mammary cancer. People who have blood stasis constitution, qi deficiency constitution and yin-deficiency constitution are more likely to suffer from depression; People who have blood stasis constitution, phlegm-dampness constitution and yin-deficiency constitution are more likely to suffer from anxiety. (目的 探索乳腺癌患者中医体质类型分布及其与焦虑抑郁状态的相关性。方法 选取了2019年7月-2020年7月507例在云南省肿瘤医院收治并就诊的乳腺癌患者, 通过问卷调查收集基线资料, 采用《中医体质量表》对其进行中医体质辨识, 采用医院焦虑抑郁量表 (HADS)评定患者的焦虑抑郁情况。结果 最终筛选得到398例乳腺癌患者。398例乳腺癌患者中医体质以平和质最多, 共136(34. 17%)例, 其次是阳虚质80(20. 10%)例, 阴虚质39(9. 80%)例, 气郁质38(9. 55%)例。抑郁患者75(18. 84%)例, 焦虑患者89(22. 36%)例。以平和质患者作为对照, 除湿热质和阳虚质外, 其余六种偏颇体质均为抑郁发病的危险因素。其中位列前三的分别是血瘀质(OR=14. 71, P<0. 001), 气虚质(OR=7. 69, P<0. 001), 阴虚质(OR=6. 20, P<0. 001); 所有偏颇体质均为焦虑发病的危险因素, 其中与焦虑发病关系最密切的前三种体质分别是: 血瘀质(OR=17. 41, P<0. 001), 阴虚质(OR=14. 05, P<0. 001), 痰湿质(OR=14. 02, P <0. 001)。结论 平和质与阳虚质是乳腺癌患者最常见的中医体质类型, 血瘀质, 气虚质, 阴虚质更容易患抑郁; 血瘀质, 痰湿质, 阴虚质更容易患焦虑。)

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