Global Pediatric Health (Apr 2024)

Vitamin D [] Insufficiency is Associated With Childhood Asthma: Recent Case-Control Findings From Bangladesh

  • Nabila Tabassum MBBS, FCPS (Pediatrics), MRCPCH,
  • Kazi Selim Anwar MD, M.Phil,
  • Probir Kumar Sarkar MBBS, MCPS (Pediatrics), DCH, FCPS (Pediatrics),
  • A. R. M. Luthful Kabir MBBS, FCPS (Pediatrics),
  • Md. Abid Hossain Mollah MBBS, FCPS (Pediatrics), Dip-Med Ed, FACP, FRCP,
  • Dipa Saha MBBS, FCPS (Pediatric Neurology),
  • Md. Jahangir Alam MBBS, DCH, MCPS (Pediatrics), FCPS (Pediatrics),
  • Mohammod Jobayer Chisti MBBS, MMed (Pediatrics), PhD (Pediatric Respiratory Medicine)

DOI
https://doi.org/10.1177/2333794X241240574
Journal volume & issue
Vol. 11

Abstract

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Objectives. To evaluate the interaction between childhood asthma and S. 25(OH) cholecalciferol among Bangladeshi children. Methods. This case control study was conducted in child asthma clinic, Bangladesh Shishu Hospital Institute during March-August 2021. Comparison was made between clinically-diagnosed (following GINA guideline) asthmatic children (2-12 years-old) (cases = 87) and age and sex-matched children having no respiratory illness (controls = 90) using SPSS’ (Statistical Package for Social Science, V.23.0 Windows) software. Results. Serum 25(OH) cholecalciferol was found to be significantly lower among the cases than the controls ( P < .01). The cases had 3.4 times higher likelihood of having low vitamin D (combined deficient + insufficient) than the controls ( P < .01). Conclusions. The results of the study demonstrate an association of Serum 25 (OH) cholecalciferol with asthma which underscores the importance of potential future trial to evaluate the efficacy of Vitamin-D supplementation for understanding the outcomes of asthmatic Bangladeshi children.