Hepatitis C virus, directly acting antivirals and Guillain-Barré syndrome

Abstract

Guillain-Barré syndrome (GBS) has been associated with both infective and noninfective etiologies. It is usually preceded by acute gastrointestinal or respiratory infections. We report an unusual case of GBS in a hepatitis C virus-positive hemodialysis (HD)-dependent patient who was being treated with sofosbuvir and daclatasvir along with antitubercular drugs for pulmonary tuberculosis. One should keep GBS in the differential diagnosis in HD patients whenever patient presents with lower limb weakness. Early diagnosis will help in timely initiation of treatment which is crucial to treat GBS.