International Journal of Molecular Sciences (Mar 2013)

Development and Antibacterial Activity of Cashew Gum-Based Silver Nanoparticles

  • Maria José dos S. Soares,
  • José Roberto S. A. Leite,
  • Carla Eiras,
  • Durcilene A. da Silva,
  • Ronaldo Z. Mendonça,
  • Selma A. S. Kuckelhaus,
  • Bruna E. F. de Faria,
  • Felipe B. Araruna,
  • Patrick V. Quelemes

DOI
https://doi.org/10.3390/ijms14034969
Journal volume & issue
Vol. 14, no. 3
pp. 4969 – 4981

Abstract

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The present study describes the development of a green synthesis of silver nanoparticles reduced and stabilized by exuded gum from Anacardium occidentale L. and evaluates in vitro their antibacterial and cytotoxic activities. Characterization of cashew gum-based silver nanoparticles (AgNPs) was carried out based on UV–Vis spectroscopy, transmission electron microscopy and dynamic light scattering analysis which revealed that the synthesized silver nanoparticles were spherical in shape, measuring about 4 nm in size with a uniform dispersal. AgNPs presented antibacterial activity, especially against Gram-negative bacteria, in concentrations where no significant cytotoxicity was observed.

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