Antacid preparations in the modern treatment of acid-base disorders

Abstract

Until the middle of the XX century, a large group of drugs called antacids played the key role in the treatment of acid-related diseases. Antacids have long been used to relieve heartburn and pain in the upper gastrointestinal tract. It would seem that with the development of pharmacology, emergence of new effective drugs like histamine H2 antagonists and proton pump inhibitors (PPIs) included in the standard treatment of gastroesophageal reflux disease and ulcer, antacids could lose their relevance. However, that is not happening. We will try here to answer such questions as why physicians continue to widely use antacids in daily practice; what are the new features of the drugs which expanded the indication spectrum.

Keywords

• кислотозависимые заболевания
• фармакотерапия
• антациды
• качество жизни
• acid-related diseases
• pharmacotherapy
• antacids
• quality of life