The effects of glycoside-rich green extract from Centella asiatica (L.) Urban on wound healing and anti-aging activity

Abstract

Background: Centella asiatica (L.) Urban extracts contain triterpenoid compounds, namely, glycosides (madecassoside and asiaticoside) and aglycones (madecassic acid and asiatic acid), that possess skincare properties. The extract with high amounts of active components could guarantee the quality of extracts for application in the cosmeceutical industry. Purpose: This study investigated the dermatological benefits of glycoside-rich green extracts from C. asiatica and different triterpenoid combinations. Methods: Six C. asiatica green extracts with different triterpenoid contents were divided into two groups: glycoside-rich extracts (GRCs), which contained >10 % glycosides, and glycoside-low extracts (GLCs), which contained 10 % glycosides has high development potential for use in the cosmeceutical industry due to its ability to promote wound healing and its antiaging properties.

Keywords

• Anti-glycation
• Apiaceae
• Cell migration
• Cosmeceuticals
• Procollagen
• Skincare