Phenyldihydropyrazolones as Novel Lead Compounds Against Trypanosoma cruzi

• Maarten Sijm,
• Julianna Siciliano de Araújo,
• Stefan Kunz,
• Susanne Schroeder,
• Ewald Edink,
• Kristina M. Orrling,
• An Matheeussen,
• Tiffany van de Meer,
• Payman Sadek,
• Hans Custers,
• Ignacio Cotillo,
• Julio J. Martin,
• Marco Siderius,
• Louis Maes,
• David G. Brown,
• Maria de Nazaré Correia Soeiro,
• GeertJan Sterk,
• Iwan J.P. de Esch,
• Rob Leurs

Affiliations

Maarten Sijm

Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Julianna Siciliano de Araújo

Laboratório de Biologia Celular, Oswaldo Cruz Institute (Fiocruz), Rio de Janeiro, Brazil

Stefan Kunz

Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Susanne Schroeder

School of Biosciences, University of Kent, Canterbury, U.K.

Ewald Edink

Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Kristina M. Orrling

Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

An Matheeussen

Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerpen, Belgium

Tiffany van de Meer

Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Payman Sadek

Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Hans Custers

Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Ignacio Cotillo

Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Julio J. Martin

Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Marco Siderius

Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Louis Maes

Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerpen, Belgium

David G. Brown

School of Biosciences, University of Kent, Canterbury, U.K.

Maria de Nazaré Correia Soeiro

Laboratório de Biologia Celular, Oswaldo Cruz Institute (Fiocruz), Rio de Janeiro, Brazil

GeertJan Sterk

Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Iwan J.P. de Esch

Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Rob Leurs

Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands