Journal of Clinical and Diagnostic Research (Feb 2019)
Panhypopituitarism without Thrombosis due Section to Primary Antiphospholipid Syndrome
Abstract
Hypopituitarism is a clinical syndrome in which pituitary hormones deficiency is seen in many conditions. Antiphospholipid Syndrome (APS) is an autoimmune disease characterised by antiphospholipid antibodies, commonly manifests as venous or arterial thrombosis with recurrent foetal loss. We here by report a case of 40-year-old female who presented with bilateral swelling of lower limbs with exertional breathlessness along with feeling of cold extremities, easy fatigability, lethargy and decreased appetite for six months which turned out to be hypopituitarism with APS. Hormone replacement was started and she experienced a good clinical improvement.
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