Dermatology Reports (Mar 2021)

Transformation of a myelodysplastic syndrome to acute myeloid leukemia and concurrent necrotizing sweet syndrome

  • Olga Vera-Lastra,
  • Arturo Olvera-Acevedo,
  • Nancy Pulido-Díaz,
  • Marissa de Jesús Quintal-Ramírez,
  • Irvin Ordoñez-González,
  • Erik Cimé-Aké,
  • María Pilar Cruz-Domínguez,
  • Gabriela Medina

DOI
https://doi.org/10.4081/dr.2021.9017
Journal volume & issue
Vol. 13, no. 1

Abstract

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The Sweet’s syndrome, is an inflammatory skin disorder characterized by extensive infiltration of neutrophils in the dermis with extension to the subcutis, known as acute febrile neutrophilic dermatosis. It may occur as a paraneoplastic syndrome. To our knowledge, there are currently few reports about transformation of a myelodysplastic syndrome to acute myeloid leukemia and concurrent necrotizing Sweet syndrome in the literature. Herein we describe an unusual case in a young patient with these characteristics that evolved to a fatal outcome.

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