Association between ABO blood groups and preeclampsia

Abstract

Objective To determine the association between the ABO blood group and preeclampsia. Methods This is a case-control study that included patients with (n = 253) and without (n = 457) preeclampsia/eclampsia in Northeastern Mexico. Data were obtained from electronic medical records. Binary multiple logistic regression analysis was used for analyzing the association between the ABO blood group and preeclampsia according to parity status while adjusting for potential confounders. Results Blood groups A, B, and AB showed adjusted odds ratios of 0.6 (95%CI 0.3-1.0), 1.1 (95%CI 0.6-2.2), and 0.3 (95%CI 0.1-1.1) in multiparous women, respectively. No association was found in nulliparous women either. Conclusions ABO blood groups were not associated with preeclampsia in Mexican women.

Keywords

• preeclampsia
• abo blood-group system
• risk factors
• association