Research progress of signaling pathways in gastric cancer metastasis

Abstract

The interaction and mutual regulation of different signaling pathways in cells form a dynamic signal transduction network, which is involved in the development of tumors, as the distant metastasis of gastric cancer is the result of regulation and influence of various signaling pathways. Cancer metastasis is often directly associated with poor prognosis, thus in-depth study of the signaling pathway affecting gastric cancer metastasis is essential strategy to optimize the treatment of advanced gastric cancer patients.

Keywords

• gastric cancer|metastasis|transforming growth factor-β(tgfβ)|phosphatidylinositol 3-kinase(pi3k)|signaling pathway