Nature Communications (Jul 2021)

Twelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in Wuhan

  • Cesheng Li,
  • Ding Yu,
  • Xiao Wu,
  • Hong Liang,
  • Zhijun Zhou,
  • Yong Xie,
  • Taojing Li,
  • Junzheng Wu,
  • Fengping Lu,
  • Lu Feng,
  • Min Mao,
  • Lianzhen Lin,
  • Huanhuan Guo,
  • Shenglan Yue,
  • Feifei Wang,
  • Yan Peng,
  • Yong Hu,
  • Zejun Wang,
  • Jianhong Yu,
  • Yong Zhang,
  • Jia Lu,
  • Haoran Ning,
  • Huichuan Yang,
  • Daoxing Fu,
  • Yanlin He,
  • Dongbo Zhou,
  • Tao Du,
  • Kai Duan,
  • Demei Dong,
  • Kun Deng,
  • Xia Zou,
  • Ya Zhang,
  • Rong Zhou,
  • Yang Gao,
  • Xinxin Zhang,
  • Xiaoming Yang

DOI
https://doi.org/10.1038/s41467-021-24230-5
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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COVID-19 pandemic is a global health risk, but our understanding on the induced durable immunity remains scarce. Here the authors assess antibody responses in 869 convalescent COVID-19 patients to find that specific antibody titers reduce with time, and the RBD-IgG positive rate exceed 70% at 12 month post diagnosis, with male and older patients showing stronger responses.