Evaluation of the in vitro antimicrobial activity of extracts of Persea americana (Avocado) variety Choquette on the growth of Staphylococcus aureus and Escherichia coli
Jhoalmis Sierra Castrillo,
Lyz J Gómez-Rave,
Adriana X Muñoz,
Faiber Ramírez-Hoyos,
Isaac Patiño-Rojas,
Santiago Zapata-Baron,
David León-Rojas,
Valmore Bermúdez-Pirela
Affiliations
Jhoalmis Sierra Castrillo
Universidad de Santander. Facultad de salud. Programa de Bacteriología y Laboratorio clínico. Grupo de investigación Biogen. Cúcuta-Norte de Santander.
Lyz J Gómez-Rave
Colegio Mayor de Antioquia. Facultad de Ciencias de la Salud, Grupo de investigación Biociencias. Medellín-Antioquia.
Adriana X Muñoz
Colegio Mayor de Antioquia. Facultad de Ciencias de la Salud. Grupo de investigación Biociencias. Medellín-Antioquia.
Faiber Ramírez-Hoyos
Universidad de Santander. Carrera de Bacteriología y Laboratorio clínico. Bucaramanga-Santander.
Isaac Patiño-Rojas
Universidad de Santander. Carrera de Bacteriología y Laboratorio clínico. Bucaramanga-Santander.
Santiago Zapata-Baron
Colegio Mayor de Antioquia, Facultad de Ciencias de la Salud. Carrera de Bacteriología y Laboratorio Clínico. Medellín-Antioquia.
David León-Rojas
Colegio Mayor de Antioquia Facultad de Ciencias de la Salud. Carrera de Bacteriología y Laboratorio Clínico. Medellín-Antioquia.
Valmore Bermúdez-Pirela
Universidad Simón Bolívar. Facultad de Ciencias de la Salud. Cúcuta-Norte de Santander.
Infectious diseases are among the leading causes of death worldwide and the situation is aggravated by the progressive emergence of resistance to conventional drug therapies. The Persea americana (avocado), has active substances that regulate the proliferation of some pathogenic microorganisms. The objective of this research was to evaluate the antimicrobial activity and minimum inhibitory concentration of extracts of Persea americana variety Choquette on the growth of S. aureus ATCC 29213 and E. coli ATCC 25922. The present was an experimental investigation using extracts of the shell, pulp and seed from organic solvents. The minimum inhibitory (MIC) and bactericidal (MIB) concentration of each extract was determined using Mueller Hinton agar plates which were inoculated with the adjusted bacterial suspension. The MIC and CMB for E. coli. Treated with the shell (hexane solvent and chloroform) was (1/2)1000 mg/ml; the MIC and CMB for S. aureus (with the solvents chloroform and ethyl acetate) was (1/2)1000 mg/ml, the pulp extract did not present antimicrobial activity for both microorganisms. The results reflect antimicrobial activity in shell and seed, so it is proposed to develop further research aimed at the characterization of these compounds for the development of antimicrobial drugs.
