European Journal of Case Reports in Internal Medicine (Mar 2020)

Urea Treatment of Syndrome of Inappropriate Antidiuretic Hormone Secretion Secondary to Amyotrophic Lateral Sclerosis

  • Francisco-Javier Mena-Martín,
  • Maria Gonzalez-Fernandez,
  • Marina Cazorla-Gonzalez,
  • Juan Carlos Martin-Escudero

DOI
https://doi.org/10.12890/2020_001444

Abstract

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Amyotrophic lateral sclerosis (ALS) rarely presents with hyponatraemia caused by syndrome of inappropriate antidiuretic hormone secretion (SIADH). We present a patient with hyponatraemia of multifactorial aetiology, in whom, after withdrawal of the drugs that contributed to this ionic alteration, SIADH secondary to ALS was confirmed. After initiating treatment with urea, sodium levels were normalized.

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