Nature Communications (Aug 2019)

An alternative framework for fluorescence correlation spectroscopy

  • Sina Jazani,
  • Ioannis Sgouralis,
  • Omer M. Shafraz,
  • Marcia Levitus,
  • Sanjeevi Sivasankar,
  • Steve Pressé

DOI
https://doi.org/10.1038/s41467-019-11574-2
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 10

Abstract

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Fluorescence correlation spectroscopy is widely used for in vivo and in vitro applications, yet extracting information from experiments still requires long acquisition times. Here, the authors exploit Bayesian non-parametrics to directly analyze the output of confocal fluorescence experiments thereby probing physical processes on much faster timescales.