Clinical and Translational Allergy (Mar 2022)

Available and affordable complementary treatments for COVID‐19: From hypothesis to pilot studies and the need for implementation

  • Jean Bousquet,
  • Tari Haahtela,
  • Hubert Blain,
  • Wienczyslawa Czarlewski,
  • Torsten Zuberbier,
  • Anna Bedbrook,
  • Alvaro A. Cruz,
  • Joao A. Fonseca,
  • Ludger Klimek,
  • Piotr Kuna,
  • Boleslaw Samolinski,
  • Arunas Valiulis,
  • Antoine Lemaire,
  • Josep M. Anto

DOI
https://doi.org/10.1002/clt2.12127
Journal volume & issue
Vol. 12, no. 3
pp. n/a – n/a

Abstract

Read online

Abstract Vaccination is a highly effective preventive measure against COVID‐19. However, complementary treatments are needed to better control the disease. Fermented vegetables and spices, agonists of the antioxidant transcription factor nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) and TRPA1/V1 channels (Transient Receptor Potential Ankyrin 1 and Vanillin 1), may help in the control of COVID‐19. Some preliminary clinical trials suggest that curcumin (spice) can prevent some of the COVID‐19 symptoms. Before any conclusion can be drawn and these treatments recommended for COVID‐19, the data warrant confirmation. In particular, the benefits of the foods need to be assessed in more patients, through research studies and large trials employing a double‐blind, placebo‐controlled design.

Keywords