The Role of Autophagy in the Female Reproduction System: For Beginners to Experts in This Field

Akitoshi Nakashima; Atsushi Furuta; Kiyotaka Yamada; Mihoko Yoshida-Kawaguchi; Akemi Yamaki-Ushijima; Ippei Yasuda; Masami Ito; Satoshi Yamashita; Sayaka Tsuda; Satoshi Yoneda; Shibin Cheng; Surendra Sharma; Tomoko Shima

doi:10.3390/biology12030373

Biology (Feb 2023)

The Role of Autophagy in the Female Reproduction System: For Beginners to Experts in This Field

Akitoshi Nakashima,
Atsushi Furuta,
Kiyotaka Yamada,
Mihoko Yoshida-Kawaguchi,
Akemi Yamaki-Ushijima,
Ippei Yasuda,
Masami Ito,
Satoshi Yamashita,
Sayaka Tsuda,
Satoshi Yoneda,
Shibin Cheng,
Surendra Sharma,
Tomoko Shima

Affiliations

Akitoshi Nakashima: Department of Obstetrics and Gynecology, Toyama Autophagy Team in Gynecology and Obstetrics, University of Toyama, Toyama 930-0194, Japan
Atsushi Furuta: Department of Obstetrics and Gynecology, Toyama Autophagy Team in Gynecology and Obstetrics, University of Toyama, Toyama 930-0194, Japan
Kiyotaka Yamada: Department of Obstetrics and Gynecology, Toyama Autophagy Team in Gynecology and Obstetrics, University of Toyama, Toyama 930-0194, Japan
Mihoko Yoshida-Kawaguchi: Department of Obstetrics and Gynecology, Toyama Autophagy Team in Gynecology and Obstetrics, University of Toyama, Toyama 930-0194, Japan
Akemi Yamaki-Ushijima: Department of Obstetrics and Gynecology, Toyama Autophagy Team in Gynecology and Obstetrics, University of Toyama, Toyama 930-0194, Japan
Ippei Yasuda: Department of Obstetrics and Gynecology, Toyama Autophagy Team in Gynecology and Obstetrics, University of Toyama, Toyama 930-0194, Japan
Masami Ito: Department of Obstetrics and Gynecology, Toyama Autophagy Team in Gynecology and Obstetrics, University of Toyama, Toyama 930-0194, Japan
Satoshi Yamashita: Department of Obstetrics and Gynecology, Toyama Autophagy Team in Gynecology and Obstetrics, University of Toyama, Toyama 930-0194, Japan
Sayaka Tsuda: Department of Obstetrics and Gynecology, Toyama Autophagy Team in Gynecology and Obstetrics, University of Toyama, Toyama 930-0194, Japan
Satoshi Yoneda: Department of Obstetrics and Gynecology, Toyama Autophagy Team in Gynecology and Obstetrics, University of Toyama, Toyama 930-0194, Japan
Shibin Cheng: Departments of Pediatrics, Women and Infants Hospital of Rhode Island, Warren Alpert Medical School of Brown University, Providence, RI 02905, USA
Surendra Sharma: Departments of Pediatrics, Women and Infants Hospital of Rhode Island, Warren Alpert Medical School of Brown University, Providence, RI 02905, USA
Tomoko Shima: Department of Obstetrics and Gynecology, Toyama Autophagy Team in Gynecology and Obstetrics, University of Toyama, Toyama 930-0194, Japan

DOI: https://doi.org/10.3390/biology12030373
Journal volume & issue: Vol. 12, no. 3
p. 373

Abstract

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Autophagy is a fundamental process involved in regulating cellular homeostasis. Autophagy has been classically discovered as a cellular process that degrades cytoplasmic components non-selectively to produce energy. Over the past few decades, this process has been shown to work in energy production, as well as in the reduction of excessive proteins, damaged organelles, and membrane trafficking. It contributes to many human diseases, such as neurodegenerative diseases, carcinogenesis, diabetes mellitus, development, longevity, and reproduction. In this review, we provide important information for interpreting results related to autophagic experiments and present the role of autophagy in this field.

Published in Biology

ISSN: 2079-7737 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General)
Website: https://www.mdpi.com/journal/biology

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