Romanian Journal of Internal Medicine (Mar 2023)

N-acetylcysteine efficacy in patients hospitalized with COVID-19 pneumonia: a systematic review and meta-analysis

  • Paraskevas Themistoklis,
  • Kantanis Anastasios,
  • Karalis Iosif,
  • Michailides Christos,
  • Karamouzos Vasileios,
  • Koniari Ioanna,
  • Pierrakos Charalampos,
  • Velissaris Dimitrios

DOI
https://doi.org/10.2478/rjim-2023-0001
Journal volume & issue
Vol. 61, no. 1
pp. 41 – 52

Abstract

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Background: N-acetylcysteine (NAC) is a mucolytic agents with anti-inflammatory properties that has been suggested as an adjunctive therapy in patients with COVID-19 pneumonia. Objectives: We conducted a systematic review and meta-analysis to evaluate available evidence on the possible beneficial effects of NAC on SARS-CoV-2 infection.

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