Медицинская иммунология (Jul 2014)

SPONTANEOUS IMMUNOGLOBULIN-SYNTHESIZING ACTIVITY OF B LYMPHOCYTES IN INFLAMMATORY RHEUMATIC DISEASES

  • A.T. T. Mamasaidov,
  • K. T. Ashirov,
  • G. M. Mamasaidova,
  • G. A. Kulchinova,
  • D. I. Abdurashitova,
  • M. Yu. Shakirov,
  • A. P. Irissov,
  • Ch. A. Eshbaeva,
  • Z. B. Nurmamatov

DOI
https://doi.org/10.15789/1563-0625-2007-4-5-527-530
Journal volume & issue
Vol. 9, no. 4-5
pp. 527 – 530

Abstract

Read online

Abstract. The aim of present work was to evaluate clinical significance of B-lymphocytes spontaneous antibody-synthesizing activity by B-lymphocytes (LASA) in patients with rheumatic inflammatory diseases (RD), i.e., reactive arthritis (ReA), ankylosing spondylitis (AS), rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE). Significantly higher LASA levels were revealed in the patients with ReA, AS, RA, and SLE, as compared with healthy persons and patients with osteoarthrosis. Clinical significance of LASA indexes and their changes may reflect manifestation and degree of immunological activities in ReA, AS, RA, and SLE.

Keywords